Jesper Tegnér, Ph.D. Professor, Strategic Chair in Computational Medicine, Head of the Unit for Computational Medicine, Center for Molecular Medicine, Dept. of Medicine, Karolinska Institute and Karolinska University Hospital.

CV

Three separate undergraduate degrees - Major in Mathematics (minor in Theoretical Physics) - Medical School@Karolinska Institute - Major in Philosophy (minor in Psychology and Linguistics); course part requirement (Pure, Applied Mathematics, and Computer Science) for a PhD in Mathematics, PhD in Medicine 1997 (7 papers in thesis, 10 PhD courses, 4 international summer schools);

Assistant Professor, Computer Science 1997-1998 (on leave 1998-2001); Visiting Scientist and Postdoctoral Fellow (USA), on a Wennergren 5 year research position 1998-2002; Alfred P Sloan Fellowship for research, US 1998-2000; Chaired Professor in Computational Biology 2002-2009; Strategic Professor and Chair in Computational Medicine 2010-

Selected publications

Five recent papers

  • Pre-B Cell to Macrophage Reprogramming Without Promoter DNA Methylation Changes. Nucleic Acid Research, November, 2011.
  • Workflow for generating competing hypothesis from models with parameter uncertainty Interface Focus, Vol 1 No3, 438-449, June 2011
  • Decoding complex biological networks – tracing essential and modulatory parameter combinations in complex and simplified models of the cell cycle. BMC Systems Biology 2011 Aug 7:5(1): 123
  • Genome-Wide System Identification and Analysis Reveals Stable yet Flexible Network Dynamics in Yeast. IET Syst. Biol. -- July 2009 -- Volume 3, Issue 4, p.219–228
  • A delay piecewise linear systems approach to modelling cell cycle regulation IET Syst. Biol. -- March 2009 -- Volume 3, Issue 2, p.113–129

    • A couple recent popular reviews

  • Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Medicine. 2011 Jul 6;3(7):43.
  • A vision and strategy for the virtual physiological human in 2010 and beyond Phil. Trans. R. Soc. A June 13, 2010 368:2595-2614;doi:10.1098/rsta.2010.0048
  • Modular analysis of disease gene networks J of Biol. 2009;8(5):48. Epub 2009 May 28.
  • Computational Disease Modeling – Fact or Fiction? BMC Syst Biol. 2009 Jun 4;3:56
  • Integrated approaches to uncovering transcription regulatory networks in mammalian cells Genomics. 91: 219–231, 2008
  • Perturbations to uncover gene networks. Trends in Genetics, Jan;23(1):34-41, 2007.

    • Other original papers include

  • Cell (2010)
  • Journal of Machine Learning Research (2007, 2009)
  • PNAS (2002, 2003, 2004, 2007, 2009)
  • Nature Genetics (2009)
  • BMC Bioinformatics (2007, 2009)
  • Science (2005)
  • PLoS Genetics (2008, 2009)
  • BMC Systems Biology (2008, 2011)
  • PLoS One (2008, 2011)

    • © 2010 | Unit of Computational Medicine | Center for Molecular Medicine | Karolinska Institutet